For example, people with diabetes may breathe with a fruity or sweet smell. The odor is caused by ketones, a chemical that is produced when the body begins to burn fat instead of glucose for energy. This is a metabolic state known as ketosis.
“The idea that exhaled breath can retain diagnostic potential has been around for some time,” said Dr. Davis. “There are reports in ancient Greek and ancient Chinese medical training textbooks that mention the use of odors as a way for doctors to guide clinical practice.”
State-of-the-art technology can detect more subtle chemical changes, and machine learning algorithms can identify patterns in breath samples from people with specific illnesses. In recent years, scientists have used these methods, lung cancer, Liver disease, tuberculosis, asthma, Inflammatory bowel disease And other conditions. (Dr. Davis and her colleagues use VOC profiles to distinguish infected cells. Various strains of influenza.. )
Prior to Covid’s hit, Breathomix was developing an electronic nose to detect several other respiratory illnesses. “We train the system.” OK, this is the smell of asthma, this is the smell of lung cancer, “said Rianne de Fries, chief technology officer and science director of the company. “That is, building a big database and finding patterns in big data.”
Last year, the company (and many other researchers in the field) pivoted and began trying to identify the breath of Covid-19. For example, during the first surge of the virus in the spring of 2020, British and German researchers collected breath samples from 98 people who appeared in hospitals with respiratory symptoms. (Participants were asked to exhale into a disposable tube, after which the researchers used a syringe to extract a breathing sample.)
Thirty-one patients were found to be infected with Covid, and the remaining patients received various diagnoses such as asthma, bacterial pneumonia, and heart failure. Researcher reported.. Breath samples from Covid-19 people had higher levels of aldehydes, compounds produced when cells or tissues were damaged by inflammation, and ketones.This is a virus Damage the pancreas And Causes ketosis..
Patients with Covid also had low levels of methanol. This may indicate that the virus has inflamed the gastrointestinal system or killed the methanol-producing bacteria that inhabit it. Combined with these breathing changes, “give us a Covid-19 signal,” said Dr. Thomas. Research co-author..
Covid test as easy as breathing
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