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What we know and what we don’t


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Omicron is the primary sequenced variant of COVID-19 in South Africa, with instances at the moment current in additional than 20 international locations and on all continents.

Named only a week in the past, it takes time to know the impression on the pandemic.

This can be a abstract of what we know and the questions surrounding the brand new model of the virus.

The place did it come from?

don’t perceive. South African epidemiologist Salim Abdool Karim states that it was first detected in Botswana and then in South Africa. Mutant Made on November twenty fifth.

On Tuesday, Dutch officers introduced on November 19, six days earlier, that people examined constructive for what was discovered to be a variant of Omicron.

Nevertheless, the World Well being Group (WHO) stated, “The instances recognized by the primary identified take a look at have been recognized from the specimens collected on November 9, 2021 with out specifying the placement.”

“In South Africa, it’s been in circulation for longer than we anticipated, most likely since early October,” stated French President Jean-Francois del Freissy. Scientific advisory board I instructed AFP.

Why is it a “concern”?

The day after South Africa’s announcement, WHO named the brand new variant after the Greek alphabet, as within the earlier model, and labeled it as a “involved” variant.

The classification is predicated on the genetic traits of Omicron and the way it behaves within the inhabitants up to now.

Omicron’s distinctive genetic construction means a number of modifications to peplomer, which may enhance the infectivity of present vaccines and make them troublesome to regulate, however these potentialities are thus far theoretical. is.

However, instances in Gauteng, South Africa, together with Johannesburg, are rising quickly, a lot of which have been recognized as Omicron.

Researchers all over the world are investigating how contagious Omicron is, the severity of the illness it causes, and whether or not it’s extra proof against the vaccine.

WHO states that this course of will most likely take a number of weeks.

Will you exchange Delta?

Delta variants are at the moment probably the most sequenced type of COVID on the earth.

Naturally competing variants that developed after the Delta (such because the lesser-known Mu and Lambda) couldn’t overtake it within the inhabitants, however the unfold of Omicron in Houten does. It means that.

On Thursday, the European Heart for Illness Management and Prevention (ECDC) stated that if the South African sample have been reproduced in Europe, Omicron might account for almost all of COVID instances inside a number of months.

Nevertheless, it’s troublesome to make a comparability with Europe at this stage, as there weren’t many deltas in South Africa.

Within the British every day The Guardian, US skilled Eric Topol stated it was not clear whether or not the Omicron epidemic was on account of “a excessive an infection like Delta, or an antigenic escape.”

Antigenic escape is when the virus can infect an individual who has already been immunized by both a earlier an infection or vaccination.

Is it extra harmful?

On Sunday, South African docs stated she had handled about 30 instances of Omicron and solely encountered “delicate signs” in these sufferers.

The scientific neighborhood has warned towards drawing conclusions based mostly on this testimony as a result of sufferers are largely younger and subsequently at low threat of significant COVID.

Thus far, all instances detected in Europe are “both asymptomatic or delicate”, based on the EDCD.

This doesn’t imply that Omicron doesn’t trigger critical COVID, but it surely leaves the door to a uncommon optimistic speculation open.

“If Omicron is extremely contagious however doesn’t trigger extreme COVID (and doesn’t fill the hospital mattress), it gives herd immunity and contributes to creating SARS-CoV-2 a benign seasonal virus. “French virologist Bruno Canard tweeted.

However he added that such a situation could be a “stroke of luck.”

How in regards to the vaccine?

Once more, it’s untimely to say whether or not the vaccine is much less efficient towards infections from Omicron and critical diseases than different variants.

“We have to see to what extent the antibodies produced by present vaccines nonetheless work and whether or not they nonetheless forestall critical sickness,” Enouf stated.

Whereas ready for real-world information, scientists try to reply this query by lab assessments.

Nevertheless, simply because vaccines will not be very efficient towards Omicron doesn’t imply that they’re fully ineffective.

Along with antibody reactions that may be dampened by mutations in Omicron, the physique has secondary T cell reactions that may be defended. Severe illness..

“We consider that the mobile response is partially efficient towards Omicron,” stated Delphi Sea.


New COVID cases in South Africa double in one day in Omicron


© 2021 AFP

Quote: Omicron: What we know and don’t know (December 2, 2021) is from https: //medicalxpress.com/information/2021-12-omicron-dont.html December 2, 2021 I obtained

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